It seems like everyone is on the vaccine bandwagon .....including the devil himself mister gates ......bill wants to rule the world i......t's been proven he owns the rights to lot's of them ......i have never trusted them .....and think there is a sinister underbelly in these concoctions....however...... there will be lot's and lot's of guinea pigs ....aka....humans that will be tested on ...you know....... the good old govt...... they will disguise this somehow to look like they care ......and give a rat's ass .......and the mass of fools will buy it .....but i think they will find something eventually ...after the election ....of course .....i know a lot of people think that this virus is a politically motivated epidemic .......i hope not .......but after all this is over...... i think everyone should sue china .....everyone ..... What if the First Coronavirus Vaccines Aren't the Best?
Professor Martin Veller (L), the Dean of the Faculty of Health Sciences at the University of the Witwatersrand (Wits University), receives an experimental vaccine for COVID-19 coronavirus at the Respiratory & Meningeal Pathogens Research Unit (RMPRU) at Chris Hani Baragwanath Hospital in Soweto on July 14, 2020. - Six senior clinicians in the Faculty of Health Sciences at Wits University have volunteered to participate in South Africas first COVID-19 vaccine trial. (Photo by Luca Sola / AFP) (Photo by LUCA SOLA/AFP via Getty Images)
Seven months into the coronavirus crisis, with more than 30 vaccines rapidly advancing through the rigorous stages of clinical trials, a surprising number of research groups are placing bets on some that have not yet been given to a single person.
The New York Times has confirmed that at least 88 candidates are under active preclinical investigation in laboratories across the world, with 67 of them slated to begin clinical trials before the end of 2021.
Those trials may begin after millions of people have already received the first wave of vaccines. It will take months to see if any of them are safe and effective. Nevertheless, the scientists developing them say their designs may be able to prompt more powerful immune responses, or be much cheaper to produce, or both — making them the slow and steady winners of the race against the coronavirus.
“The first vaccines may not be the most effective,” said Ted Ross, the director of the Center for Vaccines and Immunology at the University of Georgia, who is working on an experimental vaccine he hopes to put into clinical trials in 2021.
Many of the vaccines at the front of the pack today try to teach the body the same basic lesson. They deliver a protein that covers the surface of the coronavirus, called spike, which appears to prompt the immune system to make antibodies to fight it off.
But some researchers worry that we may be pinning too many hopes on a strategy that has not been proved to work. “It would be a shame to put all our eggs in the same basket,” said David Veesler, a virologist at the University of Washington.
In March, Veesler and his colleagues designed a vaccine that consists of millions of nanoparticles, each one studded with 60 copies of the tip of the spike protein, rather than the entire thing. The researchers thought these bundles of tips might pack a stronger immunological punch.
When the researchers injected these nanoparticles into mice, the animals responded with a flood of antibodies to the coronavirus — much more than produced by a vaccine containing the entire spike. When the scientists exposed vaccinated mice to the coronavirus, they found that it completely protected them from infection.
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